ABCB1 (MDR1)

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ABCB1 (MDR1), commonly known as P-glycoprotein (often abbreviated as P-gp or Pgp), is a member of the ABC (ATP-binding cassette) superfamily.

Pgp is extensively distributed and expressed in various tissues such as the intestinal epithelium, hepatocytes, renal proximal tubular cells, and capillary endothelial cells comprising the blood-brain barrier.

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